Magnesium...Is it the new Lyrica or a Memory Booster

By Amy Price PhD

In the spinal patient community patients have been unofficially using bio-active magnesium and benfotiamine  (along with a multi B and C supplement) for relief of CNS nerve pain along with piracetam or aniricetam to assist cognitive functioning. There is also considerable discussion on the merits of a heart healthy diet inclusive of lots of green vegetables, whole grains and lean proteins for improving cognitive function, cell repair and pain levels after spine and head injuries. Some of us have found supplementing glucosamine chondritin along with vitamin C, E and fish oil to be helpful as well, for the vegetarians flax seed oil seems to do the trick. The diet rich in magnesium may seem counterintuitive due to the brain's demand for glycogen and sweets cravings induced by chronic unremitting pain and brain fog but many have found good results with a change in diet and supplementation. In light of  this, the following  information about research on magnesium  was an interesting find.

New Israeli Research: How To Boost Memory and Avoid Memory Loss


by Baruch Gordon

(IsraelNN.com) Those who live in industrialized countries have easy access to healthy food and nutritional supplements, but magnesium deficiencies are still common. That's a problem because new research from Tel Aviv University suggests that magnesium, a key nutrient for the functioning of memory, may be even more critical than previously thought for the neurons of children and healthy brain cells in adults.

Dr. Inna Slutsky of TAU's Sackler School of Medicine published results of a 5-year probe which has significant implications for the use of over-the-counter magnesium supplements.

"We've been able to show that today's over-the-counter magnesium supplements don't really work. They do not get into the brain," says Dr. Slutsky.

Dr. Slutsky advises people to get their magnesium the old-fashioned way — by eating lots of green leaves, broccoli, almonds, cashews and fruit. The effects on memory won't appear overnight, she cautions, but with this persistent change in diet, memory should improve, and the effects of dementia and other cognitive impairment diseases related to aging may be considerably delayed.

"Our results suggest that commercially available magnesium supplements are not effective in boosting magnesium in cerebro-spinal fluid," says dr. Slutsky. "Magnesium is the fourth most abundant mineral in the body, but today half of all people in industrialized countries are living with magnesium deficiencies that may generally impair human health, including cognitive functioning."

The research focused on developing a new magnesium supplement, magnesium-L-theronate (MgT), that effectively crosses the blood-brain barrier to inhibit calcium flux in brain neurons. Begun at MIT as a part of a post-doctoral project, Dr. Slutsky's probe evolved to become a multi-center experiment with cooperation of researchers from Tel Aviv University, MIT, the University of Toronto, and Tsighua University in Beijing.

Published recently in the scientific journal Neuron, the new study found that the synthetic magnesium compound works on both young and aging animals to enhance memory or prevent its impairment.

In the study, two groups of rats ate normal diets containing a healthy amount of magnesium from natural sources. The first group was given a supplement of MgT, while the control group had only its regular diet. Behavioral tests showed that cognitive functioning improved in the rats in the first group and also demonstrated an increase of synapses in the brain — connective nerve endings that carry memories in the form of electrical impulses from one part of the brain to the other.

"We've developed a promising new compound which has now taken the first important step towards clinical trials by Prof. Guosong Liu, Director of the Center for Learning and Memory at Tsinghua University and cofounder of Magceutics company," she says.

While the effects were not immediate, the researchers in the study were able to assess that the new compound shows improved permeability of the blood-brain barrier. After two weeks of oral administration of the compound in mice, magnesium levels in the cerebral-spinal fluid increased.

"It seems counterintuitive to use magnesium for memory improvement because magnesium is a natural blocker of the NMDA receptor, a molecule critical for memory function. But our compound blocks the receptor only during background neuronal activity. As a result, it enhances the brain's 'plasticity' and increases the number of brain synapses that can be switched on," says Dr. Slutsky

Brain Development A Human Right ,

By Amy Price PhD

Clicking on Train Your Brain , Save Your Mind here will take you to a fascinating short video on the power of personal brain optimization and contains a clinically validated assessment tool. This video is presented by Dr Evian Gordon of Brain Resource Company and speaks to the highly acclaimed wellness program, My Brain Solutions. It is well worth investigating, in less than 15 days I showed improvement on several measures of cognition. If you would like to sign-up for MyBrainSolutions please email me ….read on for why training your brain matters… If you have difficulty signing up or have questions please post a comment and I will be happy to help you with this.

Research on cognition that shows transfer of training and increase in quality of life is dependent on carefully assessing individual differences with  clinically accepted tools which provide personalized training to meet these perimeters[1,2,3,4,]


Learning and novelty are partners yet many brain fitness programs offer rote repetition of weak areas without variation in task or content in a bid to target learning, However research shows us this is not the way meaningful learning occurs. Tasks must be individually challenging to hold engagement and yet structured enough to be doable. Ideally tasks will adapt to changing learning curves to build neuroplasticity. The best learning capitalizes on emotional and intellectual strengths already present while strengthening areas of weakness in a positive atmosphere. For example, teaching a university student mnemonics and concept mapping may make the memory more efficient however teaching an individual with organic damage or early dementia how to remember names and faces with a mnemonic is an exercise in futility.

Specific training alone can lead to plastic changes in the brain as demonstrated by expert Braille readers who show an enlarged hand area and smearing of finger representations in the somatosensory cortex. This result was observed in expert, but not in novice Braille readers suggesting that the training and not the blindness which leads to the changes in cortical representation [5]Similar domain specific results were noted in London taxi drivers and expert violinists. Kramer et al [6] states recruitment of additional brain regions helps performance only if the recruited area complements processing of the task in question. This is likely why rote memorization fails to increase working memory whereas training that targets attentional networks and processing speed increases working memory limits. We are incapable of processing in depth what we have not attended to and our capacity for material attended to is limited by the speed at which we process stimuli.

My Brain Solutions has an inviting Dashboard where you can  Empower Your Own Life....See you at the Dashboard!

1. Posner, M., & Rothbart M. Educating the human brain. Washington, DC US: American Psychological Association.; 2007:189-208. doi:10.1037/11519-009


2. Jaeggi SM, Buschkuehl M, Jonides J, Perrig WJ. Improving fluid intelligence with training on working memory. Proceedings of the National Academy of Sciences of the United States of America. 2008;105(19):6829-33. Available at: http://www.ncbi.nlm.nih.gov/pubmed/18443283

3. Willis SL, Tennstedt SL, Marsiske M, et al. Long-term effects of cognitive training on everyday functional outcomes in older adults. JAMA : the journal of the American Medical Association. 2006;296(23):2805-14. Available at: http://www.ncbi.nlm.nih.gov/pubmed/17179457


4. Gordon E, Arns M, Paul RH. Research Report THE INTEGRATE MODEL OF EMOTION, THINKING AND SELF REGULATION: AN APPLICATION TO THE “PARADOX OF AGING”. Thinking. 2008;7(3):367-404.

5. Greenwood PM. Functional plasticity in cognitive aging: review and hypothesis. Neuropsychology. 2007;21(6):657-73. http://www.ncbi.nlm.nih.gov/pubmed/17983277


6. Kramer AF, Bherer L, Colcombe SJ, Dong W, Greenough WT. Environmental influences on cognitive and brain plasticity during aging. The journals of gerontology. Series A, Biological sciences and medical sciences. 2004;59(9):M940-57.: http://www.ncbi.nlm.nih.gov/pubmed/15472160.

Keep Todays Memories For Tomorrow-Free Screenings

Sparks of Genius Brain Optimization Center to Hold Free Memory Screenings

National Event Stresses the Importance of Proper Detection and Treatment

Boca Raton, FL— Consumers who want a status check on their memory can take advantage of free, confidential screenings on November 17 as part of National Memory Screening Day, an annual initiative of the Alzheimer’s Foundation of America (AFA) designed to promote proper detection of memory problems and strategies for successful aging.
Memory screenings are a significant first step toward finding out if a person may have a memory problem. Memory problems could be caused by Alzheimer’s disease or other medical conditions.
Now in its seventh year, AFA’s National Memory Screening Day coincides with National Alzheimer’s Disease Awareness Month, which takes place during November.
On November 17, Sparks of Genius Brain Optimization Center will hold memory screenings at 7777 Glades Road, Boca Raton, from 10 am – 3 pm. Please call 561-859-4060 for more information or to make an appointment. You are also welcome to stop by. Refreshments will be provided.
At Sparks of Genius we offer cognitive training program which can slow down the progression of memory loss or delay it’s onset.
AFA suggests memory screenings for adults concerned about memory loss or experiencing warning signs of dementia; whose family and friends have noticed changes in them; or who believe they are at risk due to a family history of Alzheimer's disease or a related illness. Screenings also are appropriate for those who do not have a concern right now, but who want to see how their memory is now and for future comparisons.
The event features a face-to-face screening, which takes only about five to ten minutes, and consists of a series of questions and tasks. Screenings will be conducted by Dr. Rohn Kessler, Dr. Amy Price and Ninah Kessler, LCSW. The results do not represent a diagnosis, and AFA advises those individuals with below-normal scores or those who have normal scores but are still concerned to follow up with a qualified healthcare professional.
Eric J. Hall, AFA’s president and CEO, is urging consumers “to be proactive about brain health.”
”We pay so much attention to the health of our bodies, but we should be equally concerned about the health of our brains,” he said. “National Memory Screening Day offers the opportunity to find out how your memory is now and to learn how to protect it in the future.”

For more information about National Memory Screening Day, visit www.nationalmemoryscreening.org or call 866-AFA-8484.

Brain Optimization For The Job You Want!

By Ninah Kessler, Brain Fitness Coach

Can an economic downturn be good? Can it help you to recreate your life at a higher level? It can if you have the right mindset. That’s why it’s so important to teach your brain to think positively. But we also have to take care of the machinery of the brain itself. We need brain fitness.

The experts used to think that we all had a limited number of neurons in our brain. Then in the 1990’s, the decade of the brain, neuroscientists discovered that we could develop new neurons and new neuronal connections at any age. If we want to succeed in this new millennium, it behooves us to strengthen our brains.

Without help, our brains reach their peak in our twenties and then start deteriorating. By our 40’s we can usually notice a difference. It’s really very similar to what happens to our bodies. On the cognitive level, names disappear and our brains slow down. Multitasking becomes more challenging. The technical term for this is age related cognitive decline. It’s normal, but it’s not nice.

The good news is that there are things that we can do to slow down and reverse this process.

I’d like to give you an analogy from the physical world. In the 2008 Summer Olympics Dara Torres beat out women half her age to bring home silver medals. How did she do that? It wasn’t luck or chance. She created a professional training team to supercharge her body. On the everyday level, if you want to create a functional aesthetically pleasing body, you have a better chance if you work with a professional trainer or at least take a class. If you are extremely motivated, you can create your own program, but most of us do not have this level of commitment.

The key to training our brains is to expose ourselves to new and novel stimulation, continually challenging ourselves to take it to a higher level. Now we can all do this on our own to a certain degree. Crossword puzzles and suduko are good, and Nintendo DS, bridge, golf and bananagrams are even better. Traveling is great, especially if you learn a language, and playing a new musical instrument is a great neuronal enhancer. And don’t forget to eat a healthy diet, get physical exercise and decrease stress.

But the experience is enhanced with the expertise of a brain fitness coach. It is brain science to know that there are many different abilities that need training – logic, memory, attention, processing speed and mental flexibility, to name a few. Creating a training program that compensates for your weaknesses and enhances your strengths is an art.

When you’re looking for a job, you need your brain to be at its best. You need mental flexibility to figure out where the jobs are and how to format your old job qualifications into skills sets that will take you where you want to be. You need auditory processing ability and processing speed to answer questions in an interview. The best way to get these skills is with a brain fitness coach. You can even increase your brain fitness even if you’re dyslexic, have adult ADHD or a brain injury. Those with cognitive challenges often benefit the most.

A brain fitness coach can help you with stress too. It’s so easy for our thoughts to take a negative direction especially when we are looking for a job. Do you really have the luxury of wasting long periods of time in an unnecessary funk?

At Sparks of Genius, we’ve been training people to get the most out of their brains since 2001 and we have been cited as a brain fitness leader in The Wall Street Journal. You can work with your own personalized fitness coach or be part of a group. One day brain fitness coaches will be as popular as life coaches or personal trainers. But for you, that day can be now.

Ninah Kessler, LCSW, Brain Fitness Coach. SparksofGenius.com 561-859-4060

Change Your Mind With Nintendo DS

Professor Kawashima followed his dream. When he was a boy he saw himself putting his brain on a computer system. He believed that if he could represent mental functioning on a computer, he would be able to understand how people’s brains worked. On his journey he created the Nintendo DS brain training games. These games are inter-generational tools that are entertaining to people of all ages. Dr. Kawashima studied brain response with pet scans. He found when people simply watch television, brain zones that handle sound and sight respond. When playing a video game, zones that deal with motion and color respond. The part of the brain that really helps us think is called the prefrontal cortex. It is not stimulated with either of these activities.

Difficult math does not light up this part of the brain either, but simple math done under speed conditions makes a big difference. Reading silently does not use this part of the brain as much as when we read out loud. Dr. Kawashimi developed games that stimulate the prefrontal cortex. So the principle is to work out with your brain and have fun!
He came under fire because a British newspaper quoted him as saying videogames harm the brain. This is not actually true. He said videogames de-activate the prefrontal cortex. Professor Kawashima has four children. He let them all play video games but only for one hour every day. His reasoning was that sometimes the brain just needs to rest and video games were not harmful. He has done tests on elderly Japanese people. What he found was that solving mental puzzles can often arrest cognitive decline. Dr. Kawashimi says ‘I cannot comment on whether the illness of dementia is cured or not, but with these methods symptoms of dementia certainly improve”.

Other virtual activities that were once exclusively the domain of the young are being used with increasing success to rehabilitate older adults and bring them quality of life. In some senior centers card games and crossword puzzles are being replaced with virtual reality bowling or tennis. Crossword puzzles and sudoku are played in groups with computers and a mouse. These are much easier to navigate than small pieces of wood and studies have shown that simulated activities are almost as useful for practice as the real thing.

Some other scientists are jealous and treat his work with disparaging remarks such as there has not been enough time to test this or there is little empirical evidence. Other scientists like Dr. Posner are finding exciting results after only a few sessions with brain fitness tools. Scientists are testing brain games and finding increased brain fitness from the very old to the very young. Some say Professor Kawashimi is in it for the money. This is sad as all the royalties from the games and the books he wrote about the mind go entirely to the University. Dr. Kawashimi feels as a scientist it is his obligation and the obligation of others to return the results of our research to society.

This story is adapted from an article by Richard Lloyd Parry of the Times newspaper, London UK