The Spinal Injury Blues!

By Amy Price PhD

With spinal injuries and head injuries it is often the secondary damage to the neurons that causes big problems especially when that swelling and inflammation is in the spinal cord or the brain. The worst damage shows up several hours to many days later. Now, scientists in Rochester, New York, have discovered a simple way to stop a lot of this secondary damage in its tracks...at least in mice by using that old familiar blue food dye that gives M&Ms, blue bubble gum and blue raspberry popsicles their color. Patients with spinal injuries could escape with vastly reduced loss of function if this works in people but they'll turn bright blue in the process.

Much secondary damage is caused by adenosine triphosphate, or ATP. This chemical can go into overkill with trauma and cause neurons to fire until they burn out and die leaving inflammation and sludge to trip up the neurons behind them causing an unhealthy destructive cycle. With spinal trauma, the area around the injury is flooded with ATP, which causes otherwise healthy neurons to fire out of control until they die of exhaustion. It also increases the swelling around the wound. Swelling around an injury site is a positive healing factor in many parts of the body, but because the spinal cord is encased in a narrow column blood supply gets cut off and cells die. But a study published in July 28's Proceedings of the National Academy of Sciences (PNAS) seems to show that it's possible to block the actions of ATP and greatly reduce the severity and permanence of spinal injuries - using the same type of food dye that gives blue M&Ms their color, a food dye called Brilliant Blue G, or BBG.

BBG can be administered intravenously with no need to inject directly into the injury site. It has the ability to cross the blood-brain barrier, which then gives it access to the spinal cord. BBG binds to the same neuroreceptor (P2X7) as the ATP binds to but it has a stronger affinity for the receptor than ATP has and gets there first so it effectively blocks the action of the ATP at the injury site.
Only one problem....patients turn blue ! It is temporary and is sure better than having a serious injury. You wear the injury but the blue die wears off.....All I can say is color me blue for spinal injury.

See the full method of the experiments here (PDF). BBG has been a food dye approved by the FDA since the 1920s but would this be considered off label use like the cholesterol lowering of Cheerios cereal. While all the rats were severely injured, the BBG-injected rats showed a greatly improved ability to support their bodyweight on their hind legs, control their bladders, and even walk in some cases. The blue skin coloring eventually faded as well, and no side effects were noted.

Human testing would be required before BBG can be moved forward into clinical use. It would be a terrific tool for ambulance drivers and paramedics. They could begin treatment right at the site of the incident, It is cheap and easy, even hospitals can use the blue stuff as soon as they get the patient hooked up and ready to go.

The kids must have known best when they told me blue ice cream was good for me ...As for me...I will stock up on blue Gatorade and drink it down just in case it could make a difference!

Save This Brain

By Amy Price PhD

There have been multiple articles featuring brain and serious neck injury stating how people have overcome cognitive obstacles despite adversity. I celebrate these articles as I know from personal experience the tolls that this road takes and the cost to family members and supporters. One mother was explaining how one minute her brain injured son could do complex algebra and the next he could not tell a red diamond from a black spade in a deck of cards. I too remember those days.

The cognitive inconsistencies are joined by emotional areas. Sometimes the brain will forget what we want it to remember and play over and over like a broken tape those areas we only want to put behind us. The other day I found some practical help in the way of videos and research on how to navigate the initial trauma. These outline what to expect in the emergency room, how to protect yourself in the event of a crash and ways you can help yourself get the best medical care. I thought I would share them here. If you go to the web site you can download the material as MP3 or as PDF files. This is a brilliant solution as watching a video makes it tough to pick up the references which are the key to deeper study...Enjoy!

In the next few posts there will be strategies for overcoming brain fog and getting the sharp mental edge back

Your Brain On Trauma

By Amy Price PhD

Brains have axons. These are tiny fibers that are like an electronic circuit board. Axons make brain communication possible. If these are stretched past ten percent of their length they can not function and the connection is broken. To put this in perspective you can stretch your hair sixty percent beyond its length before it breaks. Broken connections mean lost function. Hair can be broken simply by running a brush through it. We seldom question the news when we are told the ninety pound teenager shook the baby to death. Yet when an adult brain is shaken by the impact of a 2500 pound car people think this could not happen. The injured are often asked if they were unconscious. The sad truth is that most brain injured people will not know if they were unconscious and will just say no.

The brain...you can build it a team can help!

Dr. Gail Denton author of the best selling book Brainlash states the Brain Injured person needs a team to restore their potential. Dr Denton wrote the first addition of this book after she sustained a brain injury. She is a successful artist, author and therapy consultant. She is presently working on research to determine the optimal brain diet and has contracted with her publisher to produce a new book featuring food for the brain and great recipes. Brain Injury does not have to be a death sentence! For helpful strategies for yourself or others take a look at this book!

Every brain injury is unique. Recovery usually does not mean returning to who and how you were before, but rather finding a new relationship to your abilities and your world. Lisa sustained a brain injury in 1993. She used her recovery to create a remarkable tool for individuals and families that struggle with brain injury. The kit was developed with Sandra J. Knutson, CRC, CDMS, CCM, Lisa’s former brain injury caseworker, and a thirty-year veteran in the brain injury recovery community. The Brain Injury Recovery Kit™ (BIRK) was created by Lisa Keller.

Try the complimentary 39 Point Learning Assessment to see if you can be set free from brain fog and live in the land of clarity! Try some free brain games to help with brain fog. CDC has published a helpful guide about what to do if you or a loved one has experienced a head injury with or without loss of consciousness. It is free http://www.cdc.gov/ncipc/tbi/tbibook.pdf

'Peace is not the absence of war....it is a deposition for benevolence, confidence and justice' (Francis Bacon)

Is There A Teen Driver in The House

Are you concerned with your teen driving a car? This concern is likely valid as teens have the highest injury and mortality rates and crashes are the leading cause of accidental death, disability and head injuries for this age group. USA today in an article last week quoted research which shows that teens with attention problems are five times as likely to get in an accident as the rest of the population.

There is equipment that can test your teen’s attention levels and improve their ability to resist distraction and stay on task. One of the programs used simulates road conditions to improve reaction time with practice before your teen gets on the road. Other programs help teens recognize their attention levels and teach them to self correct so they do not ‘space out’

They will not learn these skills in driver ed. This is a great way to equip the young driver in your household or restore skills to older drivers who see themselves as losing focus. Information about safe cars, saving your neck and how to adjust the headrest are available for free through the courtesy of the Save Your Neck Program sponsored by The Spinal Injury Foundation. Please click here for more info: http://spinalinjuryfoundation.org/neck.htm

For more information on programs to help driving skills an a free 39 point learning assessment you can take online click here

http://www.sparksofgenius.com/screens.html